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The objective of this study was to assess the influence of Ca 2+ influx on intracellular pH (pH i ) of neocortical neurons in primary culture. Neurons were exposed to glutamate (100–500 μM) or KCl (50 mM), and pH i was recorded with microspectroflurometric techniques. Additional experiments were carried out in which calcium influx was triggered by ionomycin (2 μM) or the calcium...
Information regarding human brain temperature is still rather sparse, which is surprising giving the no longer recent findings that the mammalian brain is very sensitive to minor variations in temperature. We therefore report the results of intracranial temperature monitoring in thirty neurosurgical patients. Intraventricular temperature was monitored with a thermocouple specifically designed for...
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