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Levels of the purine nucleoside adenosine (Ado) increase during conditions related to hypoxia such as inflammation, tissue damage and cancer. Ado binds to a set of G protein-linked receptors (A 1 , A 2A , A 2B and A 3 ) which are widely and differentially expressed in tissues and regulate inflammatory and autoimmune responses. We have investigated the effect of the...
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