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Summary The efficacy and safety of oral placebo or odanacatib 10, 25, or 50 mg once weekly for 52 weeks were evaluated in a double-blind, randomized, multi-center study in Japanese female and male patients with osteoporosis. Introduction Odanacatib is a selective and reversible cathepsin K inhibitor that decreases bone resorption and increases bone mineral density (BMD). Methods The primary efficacy...
This paper presents an approach to generate three-phase multi-level AC voltage output using a switching matrix device and photovoltaic (PV) panels. The approach is based on the dynamic reconfiguration of PV panels distributed in a matrix. The principle is similar to methods used in multi-level inverters related to the technique of matrix reconfiguration. The concept is to switch in and out solar panels...
A number of alkylphenolic compounds are used in a variety of commercial products and have been shown in in vitro studies to be weakly estrogenic, but in vivo data are not available addressing this issue in mammals. Human exposure to alkylphenols may occur not only from these environmental contaminants but also through contact with manufactured and metabolic breakdown products. In this study, Sprague-Dawley...
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