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Consecutive adult patients admitted to the hospital with community-acquired pneumonia from January 2000 to September 2003 were included in this prospective observational cohort study. A total of 459 patients, 259 treated with levofloxacin in single drug therapy at a dose of 500mg once a day and 209 with the combination of ceftriaxone plus clarithromycin at a dose of 2g once a day and 500mg every 12h,...