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Mice navigate nearby space using their vision and whiskers, and young mice learn to integrate these heterogeneous inputs in perceptual space. We found that cortical responses were depressed in the primary visual cortex of young mice after wearing a monocular prism. This depression was uniformly observed in the primary visual cortex and was eliminated by whisker trimming or lesions in the posterior...
A sensation of depth can arise from two-dimensional (2D) movies without any stereoscopic depth cue. Depth perception in three-dimensional (3D) space depends on the stability of stereoscopic gaze by vergence – coordinated movement of the two eyes in opposite directions – compensating the misalignment of the retinal images from the two eyes (i.e. binocular disparity) [1]. On the other hand, the oculomotor...
We investigated nociceptive cortical responses using transcranial flavoprotein fluorescence imaging in anesthetized mice with capsaicin-induced allodynia. Tactile stimuli applied to the hindpaw produced fluorescence increases in the contralateral somatosensory cortex of naïve mice. Lesioning of the ipsilateral dorsal column in the spinal cord abolished most of the cortical responses. However, the...
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