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Double-gated in-vivo small animal cone-beam micro-CT scans provide five-dimensional information about the object: the three volume dimensions plus the temporal dimensions of the respiratory motion and the heart motion, respectively. Double gating is typically performed to separate respiratory from cardiac motion when imaging the animal's lung or heart.
In classical x-ray CT the diameter of the field of measurement (FOM) must not fall below the transversal diameter of the patient or specimen. Thereby, the ratio of the the diameter of the FOM and the number of transversal detector elements typically defines the spatial resolution. We aim to improve the spatial resolution within a region of interest (ROI) by a factor of 10 to 100 while maintaining...
In patients the progression of pathologic renal processes after the treatment of primary disease is a problem of increasing importance and therapeutic strategies are insufficient till now. The aim of this paper was to search for rat models of interstitial fibrosis as a basis for testing therapeutic strategies to prevent end-stage renal failure. Experiments were done on adult female Wistar rats (Han:Wist)...
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