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In this study, we intended to differentiate patients with essential tremor (ET) from tremor dominant Parkinson disease (PD). Accelerometer and electromyographic signals of hand movement from standardized upper extremity movement tests (resting, holding, carrying weight) were extracted from 13 PD and 11 ET patients. The signals were filtered to remove noise and non-tremor high frequency components...
Vor acht Jahren gelang es erstmals, ausdifferenzierte, somatische Zellen wie kutane Fibroblasten ex vivo wieder in einen embryonalähnlichen Stammzelltyp zurückzuversetzen. Diese reprogrammierten Stammzellen könnten zum Verständnis der molekularen und zellulären Mechanismen humaner Gehirnerkrankungen sowie zur Entwicklung innovativer Interventionsstrategien beitragen.
Diagnosis and severity staging of Parkinsons disease (PD) relies mainly on subjective clinical examination. To better monitor disease progression and therapy success in PD patients, new objective and rater independent parameters are required. Surface electromyography (EMG) during dynamic movements is one possible modality. However, EMG signals are often difficult to understand and interpret clinically...
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