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Abstract: In a randomized double-masked placebo-controlled parallel-group trial 166 hysterectomized ( oophorectomy) perimenopausal and postmenopausal women aged 4555 years with a follicle stimulating hormone level above 20 IU/l were treated with one daily dose of either 0.5 mg 17-estradiol (E2), 1 mg E2, 2 mg E2 or placebo for 2 years. Bone mineral density (BMD) and biochemical bone markers were determined...
In a randomized double-masked placebo-controlled parallel-group trial 166 hysterectomized (± oophorectomy) perimenopausal and postmenopausal women aged 45–55 years with a follicle stimulating hormone level above 20 IU/l were treated with one daily dose of either 0.5 mg 17β-estradiol (E2), 1 mg E2, 2 mg E2 or placebo for 2 years. Bone mineral density (BMD) and biochemical bone markers were determined...
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