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The use of autologous chondrocyte implantation (ACI) and its further development combining autologous chondrocytes with bioresorbable matrices may represent a promising new technology for cartilage regeneration in orthopaedic research. Aim of our study was to evaluate the applicability of a resorbable three-dimensional polymer of pure polyglycolic acid (PGA) for the use in human cartilage tissue engineering...
Die Transplantation von Chondrozyten in resorbierbaren Polymervliesen ist eine vielversprechende Methode zur Behandlung von Knorpeldefekten. Die Zchtung dieser knstlichen Knorpelgewebe ist durch eine Dedifferenzierung im Monolayer, dem Einsatz von abbaubaren Matrizen und Polymeren und der erneuten Expression chondrozytrer Markergene in dreidimensionaler (3D-)Kultur gekennzeichnet. Das Ziel der vorliegenden...
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