Search results for: Howan Leung

Items from 1 to 16 out of 16 results

article

Treatment gap for convulsive status epilepticus in resource‐poor countries

Byungin Lee, the Asian Status Epilepticus Survey Group, Muzharul A. Mannan, Dong Zhou, more

The magnitude of the treatment gap (TG) for convulsive status epilepticus (CSE) in resource‐poor countries is unknown. Hospital‐based cohort studies from developing countries revealed that the management of CSE was usually suboptimal due to lack of advanced diagnostic and treatment facilities, significant delay in patient's presentation at hospital, and shortages of essential antiepileptic drugs (AEDs)...

article

Technical challenges, solutions and outcome of off-site mobile telestroke with iPad for thrombolysis in Hong Kong

Yannie Soo, Vincent Ip, K.T. Leung, Anne Chan, more

Journal of Stroke and Cerebrovascular Diseases > 2017 > 26 > 4 > 881

article

Changes of Language Function in Aphasic Stroke Survivors Receiving Bilateral Theta Burst Stimulation

Weijia He, Kathy Y.S. Lee, Thomas W.H. Leung, Howan Leung, more

Archives of Physical Medicine and Rehabilitation > 2016 > 97 > 12 > e9

article

The potential synergism by combining external counterpulsation with intermittent theta burst stimulation in post-stroke motor function recovery

Weijia He, Suk-yin Stephanie Au-Yeung, Margaret Mak, Thomas Wai Hong Leung, more

Medical Hypotheses > 2016 > 93 > C > 140-142

Upper limb weakness and incoordination is a common disability following ischemic stroke. Previous studies have showed that the single application of external counterpulsation (ECP) and intermittent theta burst stimulation (iTBS) can effectively enhance the cortical motor excitability and facilitate recovery. However, it remains uncertain if sequential application of these therapies would further augment...

article

Tooth-brushing epilepsy: A case report and literature review

David Yuen Chung Chan, Danny Tat Ming Chan, Cannon Xian Lun Zhu, Claire Ka Yee Lau, more

Clinical Neurology and Neurosurgery > 2016 > 145 > C > 46-51

•Tooth-brushing epilepsy is a type of reflex epilepsy.•In some cases, Carbamazepine or Valproate can achieve seizure control.•When seizures are intractable, surgery might achieve good outcome.•Electrocorticography allows complete excision of the epileptogenic zone.•Rolandic area lesions can be safely resected in some cases.

chapter

Management of Epilepsy in Remission

Patrick Kwan, Howan Leung, Xiaoting Hao

The Treatment of Epilepsy > Principles of Medical Management > 148 - 155

This chapter reviews the evidence base addressing some questions pertinent to deciding whether antiepileptic drug (AED) therapy should be continued in a seizure‘free patient, as well as providing practical recommendations for the drug withdrawal process. It focuses on drug withdrawal for patients who have become seizure‐free on AED treatment. The chapter discusses withdrawal of AEDs in patients entering...

article

Ictal high-frequency oscillations and hyperexcitability in refractory epilepsy

Howan Leung, Cannon X.L. Zhu, Danny T.M. Chan, Wai S. Poon, more

Clinical Neurophysiology > 2015 > 126 > 11 > 2049-2057

High-frequency oscillations (HFOs, 80–500Hz) from intracranial electroencephalography (EEG) may represent a biomarker of epileptogenicity for epilepsy. We explored the relationship between ictal HFOs and hyperexcitability with a view to improving surgical outcome.We evaluated 262 patients with refractory epilepsy. Fifteen patients underwent electrode implantation, and surgical resection was performed...

article

Evolution of intracranial atherosclerotic disease under modern medical therapy

Thomas W. Leung, Lily Wang, Yannie O. Y. Soo, Vincent H. L. Ip, more

Annals of Neurology > 77 > 3 > 478 - 486

ObjectiveUnderstanding how symptomatic intracranial atherosclerotic disease (ICAD) evolves with current medical therapy may inform secondary stroke prevention. MethodsIn a prospective academic‐initiated study, we recruited 50 patients (mean age = 63.4 ± 9.0 years) with acute strokes attributed to high‐grade (≥70%) intracranial atherosclerotic stenosis for 3‐dimensional rotational angiograms before...

article

Increasing pressure of external counterpulsation augments blood pressure but not cerebral blood flow velocity in ischemic stroke

Wenhua Lin, Li Xiong, Jinghao Han, Howan Leung, more

Journal of Clinical Neuroscience > 2014 > 21 > 7 > 1148-1152

External counterpulsation (ECP) is a noninvasive method used to augment cerebral perfusion but the optimal use of ECP in ischemic stroke has not been well documented. We aimed to investigate the effects of ECP treatment pressure on cerebral blood flow and blood pressure (BP). We recruited 38 ischemic stroke patients with large artery occlusive disease and 20 elderly controls. We commenced ECP treatment...

article

Preliminary findings of the effects of autonomic dysfunction on functional outcome after acute ischemic stroke

Li Xiong, Howan Leung, Xiang Yan Chen, Jing Hao Han, more

Clinical Neurology and Neurosurgery > 2012 > 114 > 4 > 316-320

Impaired autonomic function is common in the acute poststroke phase but little is known about its effects on functional outcome after acute ischemic stroke. This study sought to investigate the impact of autonomic dysfunction by Ewing's classification on functional outcome 2months after acute ischemic stroke.34 consecutive acute ischemic stroke patients within 7days after onset were enrolled. On admission,...

article

Prognosticating acute symptomatic seizures using two different seizure outcomes

Howan Leung, Celeste B. L. Man, Andrew C. F. Hui, Patrick Kwan, more

Epilepsia > 51 > 8 > 1570 - 1579

Purpose: This study examined the profiles and prognosis of first acute symptomatic seizure (ASS). Because seizure recurrences may occur in the setting of a persisting or reemerging acute symptomatic cause or in the setting of an unprovoked seizure, we documented the prognosis of ASS in terms of acute symptomatic seizure (AS) or unprovoked seizure (US) recurrence. Methods: We conducted a prospective...

article

Detection of the Siphon Internal Carotid Artery Stenosis: Transcranial Doppler versus Digital Subtraction Angiography

Yong You, Qing Hao, Thomas Leung, Vincent Mok, more

Journal of Neuroimaging > 20 > 3 > 234 - 239

ABSTRACT BACKGROUNDTranscranial Doppler (TCD) is widely applied to evaluate the intracranial large artery stenosis. We aimed to evaluate the accuracy of TCD in detecting siphon internal carotid artery (SICA) stenosis against digital subtraction angiography (DSA). METHODSA total of 145 patients with TCD and DSA performed were recruited. The SICA and other intracranial arteries were evaluated through transorbital and transtemporal acoustic window by TCD. We defined the best cutoff value for significant SICA stenosis by receiver‐operating characteristic (ROC) curve analyses and calculated the sensitivity, specificity, and positive and negative predictive values (PPV and NPV)....

chapter

Management of Epilepsy in Remission

Patrick Kwan, Howan Leung

The Treatment of Epilepsy > Section 2 ‐ Principles of Medical Management > 163 - 169

This chapter contains sections titled: Introduction Risk of relapse upon AED withdrawal Factors associated with seizure relapse after AED withdrawal Antiepileptic drug withdrawal after epilepsy surgery Consequences of relapse Risks associated with continuing AEDs (or benefits of withdrawal) Patient attitudes Clinical therapeutics References

article

Wavelet-denoising of electroencephalogram and the absolute slope method: A new tool to improve electroencephalographic localization and lateralization

Howan Leung, Kaspar Schindler, Anne Y.Y. Chan, Alexander Y.L. Lau, more

Clinical Neurophysiology > 2009 > 120 > 7 > 1273-1281

In ictal scalp electroencephalogram (EEG) the presence of artefacts and the wide ranging patterns of discharges are hurdles to good diagnostic accuracy. Quantitative EEG aids the lateralization and/or localization process of epileptiform activity.Twelve patients achieving Engel Class I/IIa outcome following temporal lobe surgery (1year) were selected with ∼1–3 ictal EEGs analyzed/patient. The EEG...

article

Effects of valproate or lamotrigine monotherapy on the reproductive endocrine and insulin-related metabolic profile in Chinese adults with epilepsy: A prospective randomized study

Patrick Kwan, Fung Ping Yip, Andrew C.F. Hui, Howan Leung, more

Epilepsy & Behavior > 2009 > 14 > 4 > 610-616

Cross-sectional studies have suggested that valproate treatment may be associated with hyperinsulinemia and hyperandrogenism in women. Few prospective data are available. We evaluated the reproductive endocrine and insulin-related metabolic parameters in men and women with untreated epilepsy randomized to valproate (n=44) or lamotrigine (n=37) monotherapy for 12 months. On treatment, there was no...

article

A young man who kept falling over

Edward Ho Chung Wong, Andrew C Hui, Vincent C Mok, Howan Leung, more

The Lancet > 2008 > 372 > 9636 > 418

Filter options

Publication date

Set your own date range

INFONA - science communication portal

Search results for: Howan Leung

Add recipient

Sending message cancelled

Are you sure you want to cancel sending this message?

Send message

Filter options

Publication date

Date range setting

Set the date range to filter the displayed results. You can set a starting date, ending date or both. You can enter the dates manually or choose them from the calendar.

Publication type

Keywords

Data set

Journal

Reporting an error / abuse

Sending the report failed

Accessibility options