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Introduction: This study examines hypotheses that BDL induces increased guinea pig gallbladder smooth muscle PGE 2 release by up-regulation of COX-2.Methods: BDL, Sham and Control Hartley guinea pig gallbladders were placed in cell culture, grown to confluence and underwent Western Blot analysis for smooth muscle cell content of COX-1, COX-2, Prostacylin Synthase, actin, caldesmon, vinculin,...
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