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The baroreflex-induced changes in heart rate in chloralose anaesthetized and artificially ventilated cats (2.5–4.0 kg) before and after pretreatment with calcium channel blockers (CCBs) were compared. Baroreflex mediated changes in heart rate (HR) were elicited by raising and lowering the systemic blood pressure with intravenous injections of phenyl- ephrine and sodium nitroprusside, respectively...
The effects of intravenous administration of verapamil, nifedipine and diltiazem on sympathetic stimulation-induced increase in heart rate (HR) and blood pressure (BP) have been investigated in chloralose-anaesthetized and artificially-ventilated cats. Verapamil (300 μg kg -1 i.v.) produced a significant inhibition of sympathetically-induced tachycardia and pressor responses. The same...
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