Search results for: Tamotsu Kanazawa

Items from 1 to 20 out of 24 results

article

Nuclear factor of activated T cells as a marker of in vivo low‐dose dibenzo[a,h]anthracene exposure

Cuiying He, Mengyue Shen, Kentaro Morita, Duo Wang, more

Journal of Applied Toxicology > 40 > 9 > 1239 - 1247

We previously demonstrated that particulate matter ≤2.5 μm (PM2.5) suppresses the immune response in the spleen in vivo. Although PM2.5 includes the polycyclic aromatic hydrocarbon (PAH) such as dibenzo[a,h]anthracene (DBA), it is unclear whether PAH has a direct effect on the responses of splenocytes. In our study, the concentration of DBA used was approximately 0.8 μm, which is much lower than concentrations...

article

Th2 signals are not essential for the anti‐arthritic effects of Trichinella spiralis in mice

Yoshio Osada, Kentaro Morita, Sayaka Tahara, Tsubasa Ishihara, more

Parasite Immunology > 42 > 1 > n/a - n/a

Aims Many parasitic helminths are known to alter host immune responses and consequently affect the progression of autoimmune and allergic diseases. The parasitic nematode Trichinella sp has been reported to suppress several experimental diseases in rodents, including experimental autoimmune encephalomyelitis, type 1 diabetes, colitis, airway inflammation and autoimmune arthritis. We tried to clarify...

article

Efficacy of a novel mixture of substances derived from food and food additives for controlling Dermanyssus gallinae (Mesostigmata: Dermanyssidae)

Makiko Odaka, Kazunori Matsuo, Kazumasa Ogino, Tamotsu Kanazawa, more

Applied Entomology and Zoology > 2019 > 54 > 1 > 31-38

Dermanyssus gallinae De Geer (Mesostigmata: Dermanyssidae), also known as poultry red mite, causes serious economic losses to the poultry industry worldwide. In this study, a mixture of substances derived from food and food additives (SFF), including a polysaccharide extract from laver seaweed, Pyropia yezoensis (Bangiaceae), was examined for acaricidal effects. Treatment with SFF was more effective...

article

Corrigendum to “Endocytosis of particulate matter induces cytokine production by neutrophil via toll-like receptor 4” [Int. Immunol. 57 (2018) 190–199]

Tadahiro Miyake, Duo Wang, Hidetada Matsuoka, Kentaro Morita, more

International Immunopharmacology > 2018 > 61 > C > 405

article

Cover Image

Cuiying He, Yuan Song, Takamichi Ichinose, Miao He, more

Journal of Applied Toxicology > 38 > 4 > i - i

The cover image, by Cuiying He et al., is based on the Research Article Lipopolysaccharide levels adherent to PM2.5 play an important role in particulate matter induced‐immunosuppressive effects in mouse splenocytes, DOI: 10.1002/jat.3554

article

Lipopolysaccharide levels adherent to PM2.5 play an important role in particulate matter induced‐immunosuppressive effects in mouse splenocytes

Cuiying He, Yuan Song, Takamichi Ichinose, Miao He, more

Journal of Applied Toxicology > 38 > 4 > 471 - 479

Epidemiological studies show that exposure to ambient particulate matter (PM) is associated with serious adverse health effects, including, but not limited to, those on the respiratory system. In the present study, we investigated the splenic response in mice administered PM of ≤ 2.5 μ m diameter (PM2.5). Male BALB/c mice (7 or 8 weeks old) were intratracheally administered PM2.5 (0.1 mg) four times,...

article

Dual genetic absence of STAT6 and IL-10 does not abrogate anti-hyperglycemic effects of Schistosoma mansoni in streptozotocin-treated diabetic mice

Yoshio Osada, Tomohiro Fujiyama, Naoto Kamimura, Tsukushi Kaji, more

Experimental Parasitology > 2017 > 177 > C > 1-12

Schistosoma mansoni (Sm) is known to exert protective effects against various allergic and autoimmune disorders. It has been reported that this parasite protects NOD mice from spontaneous type 1 diabetes (T1D) and ameliorates streptozotocin (STZ)-induced T1D in wild-type mice. Here, we tried to clarify the anti-diabetic mechanisms of Sm in the latter model. Sm infection partially prevented the degradation...

article

Autophagy is associated with cucurbitacin D-induced apoptosis in human T cell leukemia cells

Tsukasa Nakanishi, Yuan Song, Cuiying He, Duo Wang, more

Medical Oncology > 2016 > 33 > 4 > 1-8

We previously reported that the inflammasome inhibitor cucurbitacin D (CuD) induces apoptosis in human leukemia cell lines. In the present study, we investigated the effects of co-treatment with an additional Bcl-xL inhibitor, Z36. Treatment with Z36 induced cell death in leukemia cell lines, with MT-4 cells exhibiting the lowest sensitivity to Z36. Co-treatment of cells with Z36 and CuD resulted...

article

A rare case of paragonimiasis miyazakii with lung involvement diagnosed 7years after infection: A case report and literature review

Kazuhiro Yatera, Minako Hanaka, Tetsuya Hanaka, Kei Yamasaki, more

Parasitology International > 2015 > 64 > 5 > 274-280

We report a rare case of pulmonary paragonimiasis caused by Paragonimus miyazakii that showed pulmonary manifestations and a long-term clinical course after infection. A 45-year-old Japanese male developed cough and dyspnea in 2004 and was diagnosed with eosinophilic pneumonia. He had been treated with low-dose oral corticosteroid for 7years. He recalled that he had consumed a large amount of raw...

article

Asian sand dust causes subacute peripheral immune modification with NF‐κB activation

Yuan Song, Takamichi Ichinose, Kentaro Morita, Tsukasa Nakanishi, more

Environmental Toxicology > 30 > 5 > 549 - 558

Asian sand dust (ASD), a type of particulate matter found in Asia, migrates to East Asia. The increased airborne spread of ASD has led to concerns regarding possible adverse health effects. Our group previously reported that ASD induces lung inflammation in mice, but it is still unclear whether ASD affects lymphoid organs. In this study, we investigated the effect of ASD on splenocytes in a mouse...

article

Reciprocal effects of Schistosoma mansoni infection on spontaneous autoimmune arthritis in IL-1 receptor antagonist-deficient mice

Yoshio Osada, Sohsuke Yamada, Susumu Nakae, Katsuko Sudo, more

Parasitology International > 2015 > 64 > 1 > 13-17

Schistosome infections have been shown to prevent inflammation in induced-type arthritis models. However, its effects on spontaneous arthritis remain unknown. We here investigated the effects of Schistosoma mansoni (Sm) infection on spontaneous autoimmune arthritis in IL-1 receptor antagonist (IL-1Ra)-deficient mice. Sm infection partially reduced the severity of arthritis in male IL-1Ra-deficient...

article

Cucurbitacin D is a new inflammasome activator in macrophages

Yuan Song, Ning Ding, Tamotsu Kanazawa, Uki Yamashita, more

International Immunopharmacology > 2013 > 17 > 4 > 1044-1050

We previously reported that cucurbitacin D isolated from Trichosanthes kirilowii has anti-tumor roles to leukemia cells. However, the effect of cucurbitacin D on immune cells is not fully understood although there is no toxic activity to normal cells. In this study, immunomodulating activities of cucurbitacin D were investigated in macrophages. Cucurbitacin D could increase LPS-induced interleukin...

article

Heligmosomoides polygyrus infection reduces severity of type 1 diabetes induced by multiple low-dose streptozotocin in mice via STAT6- and IL-10-independent mechanisms

Yoshio Osada, Sohsuke Yamada, Atsunori Nabeshima, Yasunobu Yamagishi, more

Experimental Parasitology > 2013 > 135 > 2 > 388-396

Some parasitic helminths are known to protect their hosts from allergic and autoimmune disorders. Here, we tested the effects of a gastrointestinal nematode, Heligmosomoides polygyrus (Hp), on streptozotocin (STZ)-induced type 1 diabetes (T1D) in mice. Hp infection significantly suppressed hyperglycemia induced by multiple low-dose administration of STZ, but did not affect hyperglycemia induced by...

article

Neurolytic celiac plexus block reduces occurrence and duration of terminal delirium in patients with pancreatic cancer

Young-Chang P. Arai, Makoto Nishihara, Kunio Kobayashi, Tamotsu Kanazawa, more

Journal of Anesthesia > 2013 > 27 > 1 > 88-92

Purpose WHO’s three step ladder sometimes cannot provide adequate pain relief for pancreatic cancer. Some patients develop terminal delirium (TD). The aim of this study was to test if the addition of a celiac plexus block (CPB) to pharmacotherapy could reduce the incidence of TD. Methods Pancreatic cancer patients under the care of our palliative-care team were investigated with regard to the duration...

article

Corrigendum to “Schistosoma mansoni infection reduces severity of collagen-induced arthritis via down-regulation of pro-inflammatory mediators” [Int. J. Parasitol. 39 (2009) 457–464]

Yoshio Osada, Shoichi Shimizu, Takashi Kumagai, Sohsuke Yamada, more

International Journal for Parasitology > 2010 > 40 > 7 > 877

article

Identification and differentiation of human schistosomes by polymerase chain reaction

Naoko Kato-Hayashi, Masashi Kirinoki, Yukio Iwamura, Tamotsu Kanazawa, more

Experimental Parasitology > 2010 > 124 > 3 > 325-329

Recent increasing number of travelers, immigrants and foreign workers from schistosomiasis endemic area has thus resulted in the importation of schistosomiasis to non-endemic countries. To avoid ova-induced pathogenicity, sensitive and specific diagnostic means at an early stage of infection are therefore crucial. In this study, we developed polymerase chain reaction (PCR) primers specific for human...

article

Schistosoma mansoni infection reduces severity of collagen-induced arthritis via down-regulation of pro-inflammatory mediators

Yoshio Osada, Shoichi Shimizu, Takashi Kumagai, Sohsuke Yamada, more

International Journal for Parasitology > 2009 > 39 > 4 > 457-464

Various experimental and epidemiological studies have demonstrated that helminth infections affect outcomes of allergic or autoimmune disorders. Here, we examined the effects of Schistosoma mansoni infection on mouse collagen-induced arthritis, one of the most widely used animal models for rheumatoid arthritis. Male DBA/1 mice were infected with S. mansoni 2 weeks prior to being immunized with type...

article

Peroxiredoxin-1 from Schistosoma japonicum functions as a scavenger against hydrogen peroxide but not nitric oxide

Takashi Kumagai, Yoshio Osada, Nobuo Ohta, Tamotsu Kanazawa

Molecular & Biochemical Parasitology > 2009 > 164 > 1 > 26-31

Three peroxiredoxins (Prxs) are expressed during most of the developmental stages in the schistosome. Prx-1 is localized on the surface of the schistosomula and adults of Schistosoma japonicum, while Prx-2 is localized in the sub-tegumental tissues, parenchyma, vitelline glands, and gut epithelium, but not on the surface of the worms. We applied RNA interference techniques to suppress the specific...

article

2-Cys peroxiredoxins from Schistosoma japonicum: The expression profile and localization in the life cycle

Takashi Kumagai, Yoshio Osada, Tamotsu Kanazawa

Molecular & Biochemical Parasitology > 2006 > 149 > 2 > 135-143

Peroxiredoxin (Prx) is known to be an antioxidant protein that protects the organisms against various oxidative stresses and functions as a signal transductor. Here, we determined the full-length cDNA sequences of three types of Prx from an Asian blood fluke, Schistosoma japonicum: Prx-1, Prx-2 and Prx-3. According to the deduced amino acid sequences, only Prx-3 had a mitochondria-targeting sequence...

article

Early detection of Schistosoma mansoni infection by touchdown PCR in a mouse model

Tomoyuki Suzuki, Yoshio Osada, Takashi Kumagai, Atsuo Hamada, more

Parasitology International > 2006 > 55 > 3 > 213-218

A detection assay for Schistosoma mansoni DNA in mouse serum samples based on touchdown PCR was developed and evaluated. The serum samples could be assayed directly without the need to extract DNA. No cross reactions between S. mansoni and related species inducing human schistosomiasis were observed. After the infection, mouse sera and feces were collected for 8weeks. Anti-worm antigen IgG and anti-soluble...

Publication date

Set your own date range

INFONA - science communication portal

Search results for: Tamotsu Kanazawa

Nuclear factor of activated T cells as a marker of in vivo low‐dose dibenzo[a,h]anthracene exposure

Th2 signals are not essential for the anti‐arthritic effects of Trichinella spiralis in mice

Efficacy of a novel mixture of substances derived from food and food additives for controlling Dermanyssus gallinae (Mesostigmata: Dermanyssidae)

Corrigendum to “Endocytosis of particulate matter induces cytokine production by neutrophil via toll-like receptor 4” [Int. Immunol. 57 (2018) 190–199]

Cover Image

Lipopolysaccharide levels adherent to PM2.5 play an important role in particulate matter induced‐immunosuppressive effects in mouse splenocytes

Dual genetic absence of STAT6 and IL-10 does not abrogate anti-hyperglycemic effects of Schistosoma mansoni in streptozotocin-treated diabetic mice

Autophagy is associated with cucurbitacin D-induced apoptosis in human T cell leukemia cells

A rare case of paragonimiasis miyazakii with lung involvement diagnosed 7years after infection: A case report and literature review

Asian sand dust causes subacute peripheral immune modification with NF‐κB activation

Reciprocal effects of Schistosoma mansoni infection on spontaneous autoimmune arthritis in IL-1 receptor antagonist-deficient mice

Cucurbitacin D is a new inflammasome activator in macrophages

Heligmosomoides polygyrus infection reduces severity of type 1 diabetes induced by multiple low-dose streptozotocin in mice via STAT6- and IL-10-independent mechanisms

Neurolytic celiac plexus block reduces occurrence and duration of terminal delirium in patients with pancreatic cancer

Corrigendum to “Schistosoma mansoni infection reduces severity of collagen-induced arthritis via down-regulation of pro-inflammatory mediators” [Int. J. Parasitol. 39 (2009) 457–464]

Identification and differentiation of human schistosomes by polymerase chain reaction

Schistosoma mansoni infection reduces severity of collagen-induced arthritis via down-regulation of pro-inflammatory mediators

Peroxiredoxin-1 from Schistosoma japonicum functions as a scavenger against hydrogen peroxide but not nitric oxide

2-Cys peroxiredoxins from Schistosoma japonicum: The expression profile and localization in the life cycle

Early detection of Schistosoma mansoni infection by touchdown PCR in a mouse model

Filter options

Publication date

Keywords

Data set

Journal

INFONA - science communication portal

Search results for: Tamotsu Kanazawa

Add recipient

Sending message cancelled

Are you sure you want to cancel sending this message?

Send message

Filter options

Publication date

Date range setting

Set the date range to filter the displayed results. You can set a starting date, ending date or both. You can enter the dates manually or choose them from the calendar.

Keywords

Data set

Journal

Reporting an error / abuse

Sending the report failed

Accessibility options