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Tomato bushy stunt virus (TBSV) is an RNA plant virus encoding a protein of approximately 19 kDa (P19) that is involved in various activities important for pathogenicity, including virus transport and suppression of gene silencing. In this study, we provide evidence in vivo and in vitro that P19 specifically interacts with itself to predominantly form dimers, and with a novel host protein, Hin19....
Pokeweed antiviral protein (PAP), a ribosome-inactivating protein isolated from the leaves of Phytolacca americana, reveals potent antiviral activity against viruses or cytotoxic action against cells once inside the cytoplasm. Therefore PAP is a good candidate to be used as an immunotoxin. We constructed a bacterial expression plasmid encoding PAP as a fusion protein with gonadotropin-releasing hormone...
Pokeweed antiviral protein (PAP) is a soluble leaf protein produced by the plant Phytolacca americana. It is able to specifically remove an adenine residue from the 28 S ribosomal RNA of eukaryotic ribosomes, thus blocking protein synthesis. Although PAP seems to be synthesized constitutively at very high concentrations during plant development, the mechanism of its synthesis remains unclear since...
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