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To determine whether depressed or anxious patients experience greater affective change than mentally healthy individuals following influenza vaccination.Participants (n=112) completed the Positive and Negative Affect Schedule (PANAS) before influenza vaccination and 1–2days post-vaccination (M=32.3h). Pre- and post-vaccination PANAS scores were compared using two-tailed, paired-samples t-tests. Change...
BackgroundMajor depressive disorder (MDD) is a debilitating disorder characterized by widespread brain abnormalities. The literature is mixed as to whether or not white matter abnormalities are associated with MDD. This study sought to examine fractional anisotropy (FA) in white matter tracts in individuals with MDD using diffusion tensor imaging (DTI).
Methods139 participants with MDD and 39 healthy...
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