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Background The efficacy of the classical treatment modalities surgery and radiotherapy in the treatment of aggressive fibromatosis is presently disputed and there is a shift towards a more conservative approach. The aim of the present study is to objectify tumor growth in patients with extra-abdominal or abdominal wall aggressive fibromatosis, while adhering to a “watchful waiting” policy. Other objectives...
BackgroundCurrently, resection criteria for colorectal cancer liver metastases (CRCLM) are only limited by remnant liver function. Morbidity and survival after a partial hepatectomy with limited or extended indication criteria were compared.
Methods/DesignBetween 1991 and 2010, patients undergoing a liver resection for CRCLM with limited (n = 169) or extended indication criteria (n = 129) were retrospectively...
Background: For patients who present with synchronous colorectal carcinoma and colorectal liver metastasis (CRLM), a reversed treatment sequence in which the CRLM are resected before the primary carcinoma has been proposed (liver‐first approach). The aim of the present study was to assess the feasibility and outcome of this approach for synchronous CRLM.
Methods: Between 2005 and 2010, 22 patients...
Background: Plasma interleukin‐6 (IL‐6) levels increase during liver resection. The source of this IL‐6 is hitherto unclear. It has been demonstrated that the hepatosplanchnic area takes up IL‐6 but the role of the gut and liver is unknown. The aim of the present study was to investigate the role of the gut and liver in IL‐6 homeostasis during liver surgery.
Methods: Before and after partial hepatectomy,...
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