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This study examines whether renin-angiotensin-aldosterone system gene polymorphisms: ACE (encoding for angiotensin converting enzyme) c.2306-117_404 I/D, AGTR1 (encoding for angiotensin II type-1 receptor) c.1080*86A>C and CYP11B2 (encoding for aldosterone synthase) c.-344C>T are associated with the extension of coronary atherosclerosis in a group of 647 patients who underwent elective coronary...
Objectives Uridine could be a heart-specific end product of pyrimidine catabolism in humans due to absence of uridine phosphorylase activity in the heart and its presence in the other tissues. We studied the correlation between clinical indices of heart ischemia and changes in arterial concentration of uridine before and after percutaneous transluminal coronary angioplasty (PTCA).Design and Methods...
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