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6002-US-051 was a 12-week, double-blind study evaluating the safety and efficacy of istradefylline, a selective A 2A adenosine receptor antagonist, as monotherapy in patients with Parkinson's disease (PD).Patients with Hoehn–Yahr stages 1–2.5 who had not received dopaminergic drugs in the past 30 days or levodopa for >30 days at anytime were randomized to 40 mg/day istradefylline or placebo...
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