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Premenopausal women who are HCV positive (HCV+) have failing ovarian function, which is likely to impact their fertility. Thus, we investigated the reproductive history, risk of infertility, and pregnancy outcomes in women of childbearing age who were HCV+.Three different groups were studied: (1) Clinical cohort: 100 women who were HCV+ and also had chronic liver disease (CLD), age matched with 50...
Introduction: The role of Nef in human immunodeficiency virus (HIV)-1 pathogenesis has been suggested and several recent reports provided evidence that Nef enhances HIV infectivity. In vitro experiments with the nef gene have demonstrated the possible role of Nef in modulating immune responses. In addition, exogenous Nef has been demonstrated to induce proliferation of human PBMC and to enhance...
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