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Dietary supplementation with inorganic nitrate (NO3−) has been reported to improve cardiovascular health indices in healthy adults. Cigarette smoking increases circulating thiocyanate (SCN−), which has been suggested to competitively inhibit salivary nitrate (NO3−) uptake, a rate-limiting step in dietary NO3− metabolism. Therefore, this study tested the hypothesis that dietary NO3− supplementation...
Acute inflammation is the host response to infection and tissue damage, and serves to limit harm to the body. However, dysregulated or chronic inflammation underlies the pathology of many diseases, such as autoimmune disease. Elevated H 2 S levels are present in the joints of rheumatoid arthritis patients, and increased levels of H 2 S and the H 2 S synthesising enzyme CSE...
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