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Immunization is recognized as one of the most successful public health interventions ever devised. A critical component of immunization programs is the vaccine cold chain - the cold storage to keep vaccines safe from manufacture to eventual delivery to the child. Countries need to manage their vaccine cold chains and logistics systems to ensure sufficient storage capacity, distribution of adequate...
The dangers of accidental freezing of vaccines in the cold chain have prompted studies throughout the globe to better characterize the risk. To date, there has been no systematic review of these studies. This analysis highlights that accidental freezing is pervasive and occurs across all segments of the cold chain. Between 14% and 35% of refrigerators or transport shipments were found to have exposed...
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