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Calpain‐7 (CAPN7) is a unique intracellular cysteine protease that has a tandem repeat of microtubule interacting and trafficking (MIT) domains and lacks a penta‐EF‐hand domain. Although the MIT domains of CAPN7 were previously shown to interact with a subset of endosomal sorting complex required for transport (ESCRT)‐III and ESCRT‐III‐related proteins, including charged multivesicular body protein...
Calpain 7, a mammalian ortholog of yeast Cpl1/Rim13 and fungal PalB, is an atypical calpain that lacks a penta‐EF‐hand domain. Previously, we reported that a region containing a tandem repeat of microtubule‐interacting and transport (MIT) domains in calpain 7 interacts with a subset of endosomal sorting complex required for transport (ESCRT)‐III‐related proteins, suggesting involvement of calpain...
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