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REAL3 (Randomised ECF for Advanced or Locally advanced oesophagogastric cancer 3) was a phase II/III trial designed to evaluate the addition of panitumumab (P) to epirubicin, oxaliplatin and capecitabine (EOC) in untreated advanced oesophagogastric adenocarcinoma, or undifferentiated carcinoma. MAGIC (MRC Adjuvant Gastric Infusional Chemotherapy) was a phase III study which demonstrated that peri-operative...
Das Mammakarzinom ist eine heterogene Erkrankung mit einer Fülle von histologischen Typen und stark variierendem klinischen Verlauf. Die histopathologischen Klassifikationssysteme basieren auf deskriptiven Entitäten und besitzen prognostische Signifikanz. Es gibt nur wenige Prognosefaktoren, die nicht auf der histologischen Untersuchung basieren. Bislang ist nur eine sehr kleine Zahl prädiktiver Biomarker...
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