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The venom from Conus anemone contains a protein, named ANPY toxin, which displayed high affinity (IC 50 in nanomolar range) to neuropeptide Y (NPY), [Leu 31 , Pro 34 ]NPY, peptide YY, pancreatic polypeptide, the Y 1 antagonist 1229U91, and C-terminal NPY fragments. N-terminal fragments and the free acid form of NPY did not bind to ANPY. The truncated...