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Colorectal carcinoma is one of the most common types of malignancy and a leading cause of cancer related death. The aberrant expression of a brown fat‐like phenotype in cancer cells has been previously implicated in tumour growth. Therefore, the expression of brown fat‐associated proteins in colorectal cancer could be associated with tumour prognosis. Monoclonal antibodies to brown fat‐associated...
Aimsbcl‐2‐associated transcription factor 1 (BCLAF1) is a nuclear protein that binds to bcl‐related proteins and can induce apoptosis and autophagy. The aim of this study was to investigate the expression of BCLAF1 in a series of rectal cancers following neoadjuvant therapy.
Methods and resultsImmunohistochemistry was performed on a post‐neoadjuvant therapy rectal cancer tissue microarray. It contained...
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