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To assess the impact of the boost dose in patients with involved surgical margins.In the EORTC “boost versus no boost” trial, 251 patients with a microscopically incomplete tumour excision were randomised to receive either a low boost dose of 10Gy (126 patients) or a high boost dose of 26Gy (125 patients). Overall survival and the cumulative incidence of local recurrence as first event were compared...