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Non-HLA antibodies (Abs) targeting vascular receptors are considered to have an influence on renal transplant injury. Anti-endothelin-1 type A receptor (anti-ETAR) antibodies were associated with cellular and antibody-mediated rejection and early onset of vasculopathy in heart transplant patients but their role in renal transplantation remains unclear. The aim of our study was to assess the incidence...
Tętniaki aorty brzusznej (AAA, abdominal aortica neurysm) stanowią jedną z głównych przyczyn wykonywania zabiegów naczyniowych. W procesie destrukcji ściany naczynia i powstania tętniaka istotną rolę spełniają metaloproteinazy. Metaloproteazy macierzy posiadają zdolność trawienia kolagenu, fi bronektyny, elastyny, lamininy. Wzrost aktywności metaloproteinaz powoduje destrukcję macierzy pozakomórkowej...
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