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Hypoxia and HIF1α signaling direct tissue‐specific gene responses regulating tumor progression, invasion, and metastasis. By integrating HIF1α knockdown and hypoxia‐induced gene expression changes, this study identifies a melanocyte‐specific, HIF1α‐dependent/hypoxia‐responsive gene expression signature. Integration of these gene expression changes with HIF1α ChIP‐Seq analysis identifies 81 HIF1α direct...
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