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Lipocalin‐type prostaglandin D synthase (L‐PGDS) is a secretory lipid‐transporter protein that was shown to bind a wide variety of hydrophobic ligands in vitro. Exploiting this function, we previously examined the feasibility of using L‐PGDS as a novel delivery vehicle for poorly water‐soluble drugs. However, the mechanism by which human L‐PGDS binds to poorly water‐soluble drugs is unclear. In this...
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