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High out‐of‐pocket medication costs negatively impact adherence in transplantation. We evaluated the association of “medication trade‐offs”—defined as choosing to spend money on other expenses over medications—with medication nonadherence and transplant outcomes. From 2011 to 2012, we performed a prospective study of 201 transplanted recipients (n = 103 liver, n = 98 kidney and) at two large US transplant...