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Objective
Internal globus pallidus (GPi) deep brain stimulation (DBS) relieves symptoms in dystonia patients. However, the physiological effects produced by GPi DBS are not fully understood. In particular, how a single‐pulse GPi DBS changes cortical circuits has never been investigated. We studied the modulation of motor cortical excitability and plasticity with single‐pulse GPi DBS in dystonia patients...
In the human, sensorimotor integration can be investigated using combined sensory and transcranial magnetic stimulation (TMS).Short latency afferent inhibition (SAI) refers to motor cortical inhibition 20–25ms after median nerve stimulation.We investigated the influence of SAI on a local excitatory interneuronal motor cortical circuit known as short‐interval intracortical facilitation (SICF) and found...
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