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Numerical simulations of cardiovascular mass transport pose significant challenges due to the wide range of Péclet numbers and backflow at Neumann boundaries. In this paper we present and discuss several numerical tools to address these challenges in the context of a stabilized finite element computational framework. To overcome numerical instabilities when backflow occurs at Neumann boundaries, we...
A polydimethylsiloxane microchannel featuring sidewall sharp‐edge structures and bare channels, and a piezoelement transducer is attached to a thin glass slide. When an external acoustic field is applied to the microchannel, the oscillation of the sharp‐edge structures and the thin glass slide generate acoustic streaming flows which in turn rotate single cells and C. elegans in‐plane and out‐of‐plane...
On page 5120, T. J. Huang and co‐workers attach a polydimethylsiloxane microchannel featuring sidewall sharp‐edge structures and bare channels, and a piezoelement transducer, to a thin glass slide. Oscillation of polydimethylsiloxane sidewall sharp‐edge structures generates acoustic streaming flows, which in turn rotate single cells and C. elegans inside a microchannel.
Micro‐ to nanosized droplets of liquid metals, such as eutectic gallium indium (EGaIn) and Galinstan, have been used for developing a variety of applications in flexible electronics, sensors, catalysts, and drug delivery systems. Currently used methods for producing micro‐ to nanosized droplets of such liquid metals possess one or several drawbacks, including the lack in ability to control the size...
An acoustically actuated, bubble‐based technique is developed to investigate the deformability of cells suspended in microfluidic devices. On page 902, measurements of mechanical biomarkers from multiple cells made by T. J. Huang and co‐workers are conducted in a single experiment, and integrated with other bioanalysis and drug‐screening platforms. It is expected that this technique could provide...
An acoustically actuated, bubble‐based technique is developed to investigate the deformability of cells suspended in microfluidic devices. A microsized bubble is generated by an optothermal effect near the targeted cells, which are suspended in a microfluidic chamber. Subsequently, acoustic actuation is employed to create localized acoustic streaming. In turn, the streaming flow results in hydrodynamic...
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