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Acute intermittent porphyria is one of eight disorders arising from disturbances in heme biosynthesis where the precursors, 5‐aminolevulinate and porphobilinogen, are elevated in plasma and urine. Attacks are characterized by severe abdominal pain, vomiting and/or obstipation, neurological manifestations, and psychological disturbances. The mainstay of treatment is hemin infusion to induce the negative...
Aim
To investigate the acute effect of ketone ester (KE) ingestion on appetite and plasma concentrations of acyl ghrelin (AG), unacylated ghrelin (UAG) and glucagon‐like peptide‐1 (GLP‐1) secretion, and to compare responses with those elicited by isocaloric glucose (GLU) administration.
Methods
We examined 10 healthy young men on three separate occasions using a placebo (PBO)‐controlled crossover...
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