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Background The deregulation of microRNAs in both tumours and blood has led to the search for microRNAs to indicate the presence of cancer and predict prognosis. We hypothesize the deregulation of miR-200c/miR-141 in the whole blood can identify breast cancer (BC), and could be developed into a prognostic signature. Methods The expression of miR-200c and miR-141 were examined in bloods...
Most of the archived pathological specimens in hospitals are kept as formalin‐fixed paraffin‐embedded tissues (FFPE) for long‐term preservation. Up to now, these samples are only used for immunohistochemistry in a clinical routine as it is difficult to recover intact protein from these FFPE tissues. Here, we report a novel, short time‐consuming and cost‐effective method to extract full‐length, non‐degraded...
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