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Objective
To assess the efficacy of cell‐free (cf)DNA screening for aneuploidy using the automated system based on rolling circle replication.
Methods
A prospective study among women referred for invasive prenatal diagnosis between July 2018 and December 2019. The plasma fraction was extracted within 5 days from blood collection, stored at −20°C and cfDNA measured between January and December 2019...
Thyroid stimulating hormone (TSH) and free thyroxine (FT4) concentrations vary during pregnancy and conventional units can vary between laboratories. Reference ranges are widely quoted but are arbitrary and do not allow for inter-laboratory differences or gestational age. We therefore explored using multiple of the median (MoM) values to overcome these limitations.TSH and FT4 concentrations from 16,346...
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