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Objective
To detail a scoping review on the global and regional relative frequencies of oral mucosal disorders in the children based on both clinical studies and those reported from biopsy records.
Materials and Methods
A literature search was completed from 1 January 1990 to 31 December 2018 using PubMed and EMBASE.
Results
Twenty clinical studies (sample size: 85,976) and 34 studies from biopsy...
The oral mucosa's accessibility, excellent blood supply, by-pass of hepatic first-pass metabolism, rapid repair and permeability profile make it an attractive site for local and systemic drug delivery. Technological advances in mucoadhesives, sustained drug release, permeability enhancers and drug delivery vectors are increasing the efficient delivery of drugs to treat oral and systemic diseases....
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