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The longitudinal repeatability of proton MR spectroscopy (1H‐MRS) in the healthy human brain at high fields over long periods is not established. Therefore, we assessed the inter‐ and intra‐subject repeatability of 1H‐MRS in an approach suited for diffuse pathologies in 10 individuals, at 3T, annually for 3 years. Spectra from 480 voxels over 360 cm3 (∼30%) of the brain, were individually phased,...