Search results for: Joo‐Yong Jung
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Immunology > 144 > 4 > 649 - 660
Dendritic cells (DCs) are potent antigen‐presenting cells necessary to establish effective adaptive immune responses. The cytokine environment that exists at the time of DC differentiation may be an important but often ignored determinant in the phenotypic and functional properties of DCs. Interleukin‐27 (IL‐27) is a unique cytokine that has both inflammatory and immune suppressive activities. Although...
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Immunology > 139 > 4 > 484 - 493
Microbial infections are a major cause of infant mortality worldwide because of impaired immune defences in this population. The nature of this work was to further understand the mechanistic limitations of the neonatal and infant immune response. Interleukin‐27 (IL‐27) is a heterodimeric cytokine of the IL‐12 family that is produced primarily by antigen‐presenting cells and is immunosuppressive toward...
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Interleukin (IL)-27 is a unique cytokine that has a dual role in immune responses. It was originally described to promote Th1 differentiation but also suppresses inflammation by inhibiting these and other inflammatory T cell subsets. Inhibition of inflammatory activity in macrophages has also been reported. These reports have largely focused on cytokine profiles or signaling mechanisms. To date, there...
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Mycobacterium tuberculosis (MTB) remains a leading infectious threat to human health. Macrophages are the cells targeted for infection by the bacterium as well as key effector cells for clearance of the pathogen. Interleukin (IL)-27 opposes macrophage-mediated control of MTB because supplying IL-12 and blocking the activity of IL-27 limits bacterial growth in primary human macrophages. The purpose...
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Microwave and Optical Technology Letters > 52 > 12 > 2636 - 2639
This article presents a flexible RF transmitter module based on flexible printed circuit board (FPCB).The polyimide with micro‐machining fabrication technique is employed for realization of FPCB to achieve the high flexibility as well as low loss at microwave frequency band. The active devices in the proposed flexible RF transmitter are design with InGaP/GaAs hetero‐junction bipolar transistor monolithic...
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