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In a pilot randomized clinical trial of active stellate ganglion blockade (SGB) versus sham control, SGB significantly reduced the frequency of reported moderate to severe vasomotor symptoms (VMS) and the frequency of physiologic VMS measured using ambulatory skin conductance monitors. Here we examine secondary effects of SGB on verbal learning and memory.In a randomized, sham-controlled study, 36...
ScopeWomen seeking alternatives to hormone‐replacement therapy for menopausal symptoms often try botanical dietary supplements containing extracts of hops (Humulus lupulus L.). Hops contain 8‐prenylnaringenin (8‐PN), a potent phytoestrogen, the related flavanones 6‐prenylnaringenin and isoxanthohumol (IX), and the prenylated chalcone xanthohumol (XN).
Methods and resultsAfter chemically and biologically...
The performance of a clinical trial for pharmaceutical agents is usually undertaken only after there is likely benefit demonstrated from the use of the putative agent. The consideration of botanical products as pharmaceutical agents must similarly go through a rigorous evaluation process. The present work reviews the recently published phase II study evaluating the effectiveness of black cohosh and...
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