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Objective
Melatonin improves hepatic perfusion after hemorrhagic shock and may reduce stress‐induced gastric lesions. This study was designed to investigate whether pretreatment with melatonin may influence gastric mucosal microcirculatory perfusion (μflow), oxygenation (μHbO2), or intestinal barrier function during physiological and hemorrhagic conditions in dogs.
Methods
In a randomized crossover...