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Background: Pro‐inflammatory cytokines, such as tumour necrosis factor (TNF)‐α, are known to be involved in the establishment of insulin resistance. Insulin resistance plays a key role in the development of obesity‐related pathologies, such as type 2 diabetes and non‐alcoholic fatty liver disease (NAFLD). The state of chronic inflammation associated with obesity led us to hypothesize that TNF‐α blockade...