The Infona portal uses cookies, i.e. strings of text saved by a browser on the user's device. The portal can access those files and use them to remember the user's data, such as their chosen settings (screen view, interface language, etc.), or their login data. By using the Infona portal the user accepts automatic saving and using this information for portal operation purposes. More information on the subject can be found in the Privacy Policy and Terms of Service. By closing this window the user confirms that they have read the information on cookie usage, and they accept the privacy policy and the way cookies are used by the portal. You can change the cookie settings in your browser.
Climate change and pollution impact those alive today as well as future generations, suggesting that attitudes toward future generations may be linked with environmental attitudes. Despite the widespread impact of the environmental on human lives, there is considerable partisan divide in the United States with regards to environmental issues. We investigated relationships between political conservatism,...
Introduction: TGF-beta isoforms are a multifunctional set of protein that regulates cell proliferation, differentiation and extracellular matrix synthesis. A few studies have suggested a role for TGF-beta in pancreatic organogenesis. We studied TGF beta signaling in the developing pancreas using ontogenic and inhibitory studies.Methods: Dorsal embryonic pancreatic rudiments were either harvested fresh...
Introduction: TGF-beta signaling has been implicated in pancreatic cancer due to the prevalence of smad4 mutations. An established model for pancreatic endocrine differentiation is exendin-4 (glucagon-like peptide-1 analog) treatment of AR42J cells (rat pancreatic carcinoma cell line). We studied TGF-beta superfamily signaling and downstream intracellular effectors (smad proteins) implicated in many...
Introduction: During embryogenesis, developing organs are in direct apposition to one another. The coelomic epithelium (peritoneal anlage) has barrier properties and its removal adversely affects development. We hypothesize that coelomic epithelium contains signals within a developing organ to prevent inappropriate attenuation of signals.Methods: Pancreas was harvested from day 11 mouse embryos. Several...
Set the date range to filter the displayed results. You can set a starting date, ending date or both. You can enter the dates manually or choose them from the calendar.