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Seventy‐two novel human leukocyte antigen (HLA) class I and class II alleles are described from volunteers for the ‘Be The Match Registry®’: 17 HLA‐A alleles, 12 HLA‐C alleles, 31 HLA‐B alleles and 12 HLA‐DRB1 alleles. Forty‐six (∼64%) of the 72 novel alleles are single‐nucleotide substitution variants when compared with their most homologous allele. Five of these single‐nucleotide variants are silent...
Twenty‐one novel human leukocyte antigen (HLA) class I and class II alleles are described: seven HLA‐A alleles, five HLA‐C alleles, five HLA‐B alleles and four HLA‐DRB1 alleles. Seventeen (∼81%) of the 21 novel alleles are single nucleotide substitution variants when compared with their most homologous allele. Nine of these single nucleotide variants cause an amino acid substitution, while eight are...
Seventy‐eight novel human leukocyte antigen (HLA) class I and class II alleles are described: 19 HLA‐A alleles, 30 HLA‐C alleles, 21 HLA‐B alleles, 7 HLA‐DRB1 alleles and 1 HLA‐DPB1 allele. Eight (∼10%) of the novel alleles were found in more than one individual and may be more common in the population. Sixty‐two (∼80%) of the 78 novel alleles are single nucleotide substitution variants when compared...
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