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ObjectiveCharacterize glutamate neurotransmission in the hippocampus of awake‐behaving rodents during focal seizures in a model of aging.
MethodsWe used enzyme‐based ceramic microelectrode array technology to measure in vivo extracellular tonic glutamate levels and real‐time phasic glutamate release and clearance events in the hippocampus of awake Fischer 344 rats. Local application of 4‐aminopyridine...