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Background and purpose
The modifiable risk factor cigarette smoking has been associated with an increased risk of developing multiple sclerosis (MS) and with disease activity in relapsing−remitting MS. However, less is known about the effect of smoking on disease progression in progressive MS. Here the association between cigarette smoking and disability accumulation in primary progressive MS (PPMS)...
A method of tuning for PI controllers with one-way lead/lag decoupling tuning is demonstrated for 2x2 input-output systems, based on finite frequency response data. The frequency response estimates are obtained from closed loop tests using an identification technique based on bandpass filters. The open-loop frequency response is calculated and used to tune PI controllers and to fit lead-lag compensators...
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