Search results for: A. Meretoja

Items from 1 to 16 out of 16 results

article

Diabetes and intracerebral hemorrhage: baseline characteristics and mortality

R. Liebkind, D. Gordin, D. Strbian, A. Meretoja, more

European Journal of Neurology > 25 > 6 > 825 - 832

Background and purpose Acknowledging the conflicting evidence for diabetes as a predictor of short‐ and long‐term mortality following an intracerebral hemorrhage (ICH), we compared baseline characteristics and 30‐day and long‐term mortality between patients with and without diabetes after an ICH, paying special attention to differences between type 1 (T1D) and type 2 (T2D) diabetes. Methods Patients...

article

Diabetes and intracerebral hemorrhage: baseline characteristics and mortality

R. Liebkind, D. Gordin, D. Strbian, A. Meretoja, more

European Journal of Neurology > n/a - n/a

article

Beta‐blocker therapy is not associated with mortality after intracerebral hemorrhage

M. Sykora, J. Putaala, A. Meretoja, T. Tatlisumak, more

Acta Neurologica Scandinavica > 137 > 1 > 105 - 108

Background Beta‐blocker therapy has been suggested to have neuroprotective properties in the setting of acute stroke; however, the evidence is weak and contradictory. We aimed to examine the effects of pre‐admission therapy with beta‐blockers (BB) on the mortality following spontaneous intracerebral hemorrhage (ICH). Methods Retrospective analysis of the Helsinki ICH Study database. Results A...

article

Comparing ischaemic stroke in six European countries. The EuroHOPE register study

A. Malmivaara, A. Meretoja, M. Peltola, D. Numerato, more

European Journal of Neurology > 22 > 2 > 284 - e26

Background and purposeThe incidence of hospitalizations, treatment and case fatality of ischaemic stroke were assessed utilizing a comprehensive multinational database to attempt to compare the healthcare systems in six European countries, aiming also to identify the limitations and make suggestions for future improvements in the between‐country comparisons. MethodsNational registers of hospital...

article

Incidence, risk factors, etiology, severity and short‐term outcome of non‐traumatic intracerebral hemorrhage in young adults

R.‐J. Koivunen, J. Satopää, A. Meretoja, D. Strbian, more

European Journal of Neurology > 22 > 1 > 123 - 132

Background and purposeIntracerebral hemorrhage (ICH) is a common and severe form of stroke but is scarcely studied in young adults. Our aim was to study risk factors, clinical presentation and early mortality of ICH in the young and compare these features with older patients. MethodsAll consecutive patients aged between 16 and 49 diagnosed with a first‐ever ICH at the Departments of Neurology or...

article

In‐hospital cardiac complications after intracerebral hemorrhage

J. Putaala, M. Lehto, A. Meretoja, K. Silvennoinen, more

International Journal of Stroke > 9 > 6 > 741 - 746

Background and purposeData on cardiac complications and their precipitants after intracerebral hemorrhage are scarce. We examined the frequency and risk factors for serious in‐hospital cardiac events in a large cohort of consecutive intracerebral hemorrhage patients. MethodsA retrospective chart review of 1013 consecutive patients with nontraumatic intracerebral hemorrhage treated at the Helsinki...

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Higher baseline international normalized ratio value correlates with higher mortality in intracerebral hemorrhage during warfarin use

S. Curtze, D. Strbian, A. Meretoja, J. Putaala, more

European Journal of Neurology > 21 > 4 > 616 - 622

Background and purposeIntracerebral hemorrhage (ICH) is the most feared complication of oral anticoagulation (OAC). Our aim was to investigate the impact of the international normalized ratio (INR) level on mortality in OAC‐associated ICH compared with non‐OAC‐associated ICH. MethodsA retrospective chart review of consecutive ICH patients treated at the Helsinki University Central Hospital from January...

article

Lost potential of kidney and liver donors amongst deceased intracerebral hemorrhage patients

T. Sairanen, A. Koivisto, A.‐M. Koivusalo, K. Rantanen, more

European Journal of Neurology > 21 > 1 > 153 - 159

Background and purposeIntracerebral hemorrhage (ICH) has high acute mortality. The number of potential kidney and liver donors amongst deceased ICH patients was estimated to improve our institutional guidelines on acute care of neurocritical patients to increase organ donation. MethodsA chart review was carried out by a multi‐professional team for consecutive ICH patients admitted to the emergency...

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Hemiplegia and thrombolysis

A. Meretoja, D. Strbian, J. Putaala, M. Kaste, more

European Journal of Neurology > 19 > 9 > 1235 - 1238

Background and purposeHemiplegia at stroke onset may be considered a contraindication for thrombolytic therapy. We describe the outcome of patients with ischaemic stroke presenting with hemiplegia and treated with intravenous alteplase (tPA). MethodsAll patients treated with tPA for acute ischaemic stroke between 1995 and 2010 were prospectively recorded in the Helsinki Stroke Thrombolysis Registry...

article

Neuromuscular block and current treatment strategies for its reversal in children

OLLI A. MERETOJA

Pediatric Anesthesia > 20 > 7 > 591 - 604

Even though neuromuscular blocking agents are an essential part of balanced anesthesia and the risks of residual paralysis are well documented, many anesthetists seldomly monitor neuromuscular block. Classical reversal agent neostigmine is unable to antagonise a deep neuromuscular block and is rather slow to antagonise even a moderate block. These caveats may have introduced a practice to use muscle...

article

The Air-Leak Test Is Not a Good Predictor of Postextubation Adverse Events in Children Undergoing Cardiac Surgery

Pertti K. Suominen, Netta A. Tuominen, Jukka T. Salminen, Reijo E. Korpela, more

Journal of Cardiothoracic and Vascular Anesthesia > 2007 > 21 > 2 > 197-202

Objective: The air-leak test is recommended as a method of assessing the appropriate size of an uncuffed endotracheal tube (ETT) in children. The authors’ primary objective was to determine whether the air-leak test would predict adverse events and reintubations after the removal of the ETT in children who have undergone cardiac surgery.Design: Prospective, observational, clinical study.Setting: University...

article

Pharmacokinetics and pharmacokinetic-dynamic modelling of rocuronium in infants and children

J M Wierda, O A Meretoja, T Taivainen, J H Proost

British Journal of Anaesthesia > 1997 > 78 > 6 > 690-695

We have determined the pharmacokinetics and pharmacokinetic-pharmacodynamic relationship of rocuronium in infants and children. We studied infants (n = 5, 0.1-0.8 yr) and children (n = 5, 2.3-8 yr), ASA II, in the ICU while undergoing artificial ventilation under i.v. anaesthesia with an arterial cannula in situ and the EMG of the adductor pollicis muscle was monitored. Rocuronium 0.06 (infants) and...

article

Pipecuronium Revisited: Dose-Response and Maintenance Requirement in Infants, Children, and Adults

Olli A. Meretoja, Olli Erkola

Journal of Clinical Anesthesia > 1997 > 9 > 2 > 125-129

Study Objective: To compare dose-response relationship and maintenance requirement of pipecuronium in anesthetized infants, children, and adults.Design: Prospective, consecutive sample trial.Setting: Operating room at a university hospital.Patients: 15 infants (1-11 months), 15 children (3-10 years), and 15 adults (35-50 years) of ASA physical status I and II.Interventions: Anesthesia was induced...

article

Sevoflurane-nitrous oxide or halothane-nitrous oxide for paediatric bronchoscopy and gastroscopy

O A Meretoja, T Taivainen, L Räihä, R Korpela, more

British Journal of Anaesthesia > 1996 > 76 > 6 > 767-771

We have studied 120 infants and children, in three age groups (3-11 months, 1-5 yr and 6-15 yr), to compare anaesthesia with sevoflurane or halothane for bronchoscopy or gastroscopy, or both. Premedication or i.v. anaesthetic agents were not used. Patients were allocated randomly to receive either 7% sevoflurane or 3% halothane in 66% nitrous oxide in oxygen for induction of anaesthesia. The same...

article

Potency of Doxacurium in Infants, Children, and Adolescents during N ₂ O-O ₂ -Alfentanil Anesthesia

Tomi R. Taivainen, Olli A. Meretoja

Journal of Clinical Anesthesia > 1996 > 8 > 3 > 225-228

Study Objective: To evaluate neuromuscular potency of doxacurium during balanced anesthesia in pediatric patients.Design: Prospective, consecutive sample trial.Setting: Operating room at a university hospital.Patients: 15 infants (1 to 11 months), 20 children (3 to 10 years), and 20 adolescents (13 to 19 years).Interventions: Anesthesia was induced and maintained with thiopental, alfentanil, and nitrous...

article

Time course of potentiation of mivacurium by halothane and isoflurane in children

O A Meretoja, K Wirtavuori, T Taivainen, K T Olkkola

British Journal of Anaesthesia > 1996 > 76 > 2 > 235-238

We studied 40 children, aged 1-15 yr, to analyse the time course of potentiation of mivacurium produced by halothane and isoflurane. A steady infusion requirement of mivacurium to maintain 90% neuromuscular block was established during thiopentone-alfentanil-nitrous oxide-oxygen anaesthesia. Patients were then allocated randomly to receive 1 MAC end-tidal concentration of either halothane (group Hal)...

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