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By using a catalytic amount of a porphyrin‐based covalent organic framework (Por‐Ad‐COF) as the efficient recyclable photocatalyst, the photocatalytic oxidative [3+2] cycloaddition reaction between tetrahydroisoquinolines and N‐substituted maleimides was developed under aerobic conditions at room temperature. Various substituted pyrrolo[2,1‐a]isoquinolines were obtained in moderate to good yields...
Despite the significance of cigarette smoke for carcinogenesis, the molecular mechanisms that lead to increased susceptibility of human cancers are not well-understood. In our present study, the oncogenic transforming effects of cigarette smoke condensate (CSC) were examined using papillomavirus-immortalized human bronchial epithelial cells (BEP2D). Growth kinetics, saturation density, resistance...
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