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Aim
To evaluate long‐term outcomes and prognostic factors of non‐reconstructive surgical treatment of peri‐implantitis.
Materials and Methods
One hundred forty‐nine patients (267 implants) were surgically treated for peri‐implantitis and followed for an average of 7.0 (SD: 3.6) years. The primary outcome was implant loss. Additional bone loss and surgical retreatment were secondary outcomes. Patient/implant...
Constitutive activation of the PI3K/AKT/mTOR‐pathway plays an important role in the pathogenesis of mantle cell lymphoma (MCL), leading to approval of the mTOR inhibitor temsirolimus for relapsed or refractory MCL. Yet, despite favorable initial response rates, early relapses under treatment have been observed. Therefore, understanding the underlying mechanisms of temsirolimus resistance and developing...
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