The Infona portal uses cookies, i.e. strings of text saved by a browser on the user's device. The portal can access those files and use them to remember the user's data, such as their chosen settings (screen view, interface language, etc.), or their login data. By using the Infona portal the user accepts automatic saving and using this information for portal operation purposes. More information on the subject can be found in the Privacy Policy and Terms of Service. By closing this window the user confirms that they have read the information on cookie usage, and they accept the privacy policy and the way cookies are used by the portal. You can change the cookie settings in your browser.
Anticancer vaccine: Antigen 2 made out of a tripeptide of β‐D‐Galp‐(1→3)‐CH2‐α‐D‐GalNAc‐O‐Ser and conjugated with keyhole limpet hemocyanin (KLH) protein induced an early and strong immune response (IgG antibodies) in mice. Antigen 3 made out of an α‐C‐galactoside analogue did not induce such an immune response (see scheme).
FK866 (also named APO866 or WK175) is a potent NAMPT inhibitor being evaluated (Phase II) as a potential anticancer drug. The preparation of the C‐iminoribofuranoside analog (2E)‐N‐[4‐(1‐benzoylpiperidin‐4‐yl)butyl]‐3‐{3‐[(2S,3S,4R,5R)‐3,4‐dihydroxy‐5‐(hydroxymethyl)pyrrolidin‐2‐yl]phenyl}prop‐2‐enamide ((−)‐1) is reported.
Set the date range to filter the displayed results. You can set a starting date, ending date or both. You can enter the dates manually or choose them from the calendar.