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To discover novel laccase inhibitors as potential fungicides, twenty‐six novel L‐menthol hydrazide derivatives were designed and synthesized. In the in vitro antifungal assay, most of the target compounds displayed pronounced antifungal activity against Sclerotinia sclerotiorum, Fusarium graminearum, and Botryosphaeria dothidea. Especially, the EC50 of compounds 3 b and 3 q against B. dothidea was...
BACKGROUND
To explore further potential natural product‐based antifungal agents, a series of novel nopol‐based carboxamide and hydrazide derivatives containing a natural pinene structure were designed, synthesized, and evaluated for their inhibitory activities against seven phytopathogenic fungi and oomycetes.
RESULTS
The bioassay results indicated that some compounds exhibited good inhibitory...
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